For women, things are a bit different. They do not need SERMs because they produce so little testosterone naturally that suppression isn’t as detrimental. However, Anavar and Winstrol act much like testosterone in the female body, and using the combination over the course of four to six weeks can create a hormonal imbalance. Women who simply come off steroids cold turkey, even after a few weeks, may notice undesirable effects like fatigue and irritability. To avoid this, simply reducing dose toward the end of the cycle can help tremendously.
Tbol is C17 AA, or it is alpha alkylated at carbon 17. This is a major distinction among oral steroids, and is actually what separates them as a class from something like proviron, which we would not consider an "oral" because it does NOT have this methyl group added at carbon 17. This added methyl group allows the oral steroid to somewhat bypass the liver and first pass metabolism and get into your bloodstream. This stresses the liver, as it has mechanisms which if it fails to metabolize something, tbol in this case, it releases enzymes and what not in order to attempt to metabolize this drug faster. This is essentially why liver enzymes raise while on oral steroids, and which is why TUDCA is recommended.