Initial doses of mg/kg/day rounded to the nearest available patch strength (patches are available in 3 strengths delivering doses of approximately , , or mg/day over 7 days) were used in a small study including 7 pediatric patients (age range 5 to 12 years, weight range to kg). Patients weighing less than 25 kg were started on half a mg/day patch for 3 days to minimize adverse reactions. The mean dose of clonidine used in the study was +/- mg/day. Although patches in this study were changed every 7 days, other authors have suggested that pediatric patients may require patches be changed earlier (., every 5 days) due to variable absorption. Partial doses of patches may be administered by placing impermeable material (., adhesive bandage) on the skin under the patch proportionate to the desired dose reduction.
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID). It is also known as NUROFEN, FENPAED.