Steroid myopathy muscle biopsy

EXPECTED COURSE AND PROGNOSIS
• Prognosis is poor for resolution of myotonia in patients with hyperadrenocorticism
• Prognosis good for return of muscle strength and mass with steroid myopathy
• Improvement in muscle pain and stiffness likely with hypothyroid myopathy
• Prognosis good for return of muscle strength in feline hyperthyroidism with return to euthyroid state
• Prognosis good for return of muscle strength with hypoadrenocorticism
• Dysphagia and regurgitation may resolve with adequate treatment

Neuroactive steroids are also called as neurosteroids . They are endogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors. Neuroactive steroid refers to steroids that are synthesized by an endocrine gland that reach the brain through the bloodstream and have effects on brain function. Neurosteroids have a wide range of potential clinical applications from sedation to treatment of epilepsy and traumatic brain injury. Ganaxolone is a synthetic analog of the endogenous neurosteroid. Allopregnanolone is under investigation for the treatment of epilepsy.

Steroid myopathy muscle biopsy

steroid myopathy muscle biopsy

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